NDUFS8

Across TCGA cell cohorts, NDUFS8 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,135 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NDUFS8-associated GO terms across cancer lineages are CAAX-box protein processing, Positive regulation of type B pancreatic cell development, and Proton motive force-driven ATP synthesis. Each is linked with NDUFS8 in more than 10 cancer types. Because this analysis shows association rather than direction, both NDUFS8-to-partner and partner-to-NDUFS8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CAAX-box protein processing grouped by NDUFS8-low versus NDUFS8-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS8→partner) and Y-score (partner→NDUFS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	CAAX-box protein processing →	+0.198	+0.950	<.001	<.001	3	11
SOFT_TISSUE	Positive regulation of type B pancreatic cell development →	+0.267	+0.640	.002	<.001	3	9
BLOOD_Leukemia	Proton motive force-driven ATP synthesis →	+0.053	+0.317	.002	.003	3	8
SKIN	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.086	+0.457	<.001	.008	2	8
SKIN	Electron transport coupled proton transport →	+0.086	+0.457	<.001	.008	2	8
URINARY_TRACT	Leukocyte migration →	-0.107	-0.698	.007	.007	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,135 associations by consensus.

CAAX-box protein processing by NDUFS8 expression — BONE

Explore this box plot interactively →