NDUFS7

Across TCGA pan-cancer cohorts, NDUFS7 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NDUFS7 data layer compared with 18 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher NDUFS7 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated NDUFS7 expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

PDAC, CCRCC, and LSCC are the cancer types where NDUFS7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	II,III,IV	0.653	0.414	.002	31	view →
CCRCC	OS	Median	II,III,IV	0.826	0.628	.018	18	view →
LSCC	DFS	Quartile	II,III,IV	1.000	0.698	.001	16	view →
LUAD	DFS	Quartile	All	0.375	0.670	.037	5	view →
GBM	DFS	Median	All	0.808	0.636	.015	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NDUFS7–PDAC (OS)

Open the PDAC breakdown →