NDUFS6

Across TCGA pan-cancer cohorts, NDUFS6 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NDUFS6 data layer compared with 27 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher NDUFS6 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NDUFS6 expression acts as an unfavorable survival marker.

THYM and STAD are the cancer types where NDUFS6 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	All	0.039	0.928	<.001	24	view →
STAD	OS	Median	All	0.224	0.729	.007	18	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

NDUFS6–THYM (OS)

Open the THYM breakdown →