NDUFS6

Across TCGA patient cohorts, NDUFS6 mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible NDUFS6-associated genes across cancer lineages are RNA5SP413, MIR6133, and CYCSP35. Each is linked with NDUFS6 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFS6-to-partner and partner-to-NDUFS6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP413 grouped by NDUFS6-low versus NDUFS6-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS6→partner) and Y-score (partner→NDUFS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP413 →	+1.256	+5.081	<.001	.004	3	2
UCEC	MIR6133 →	+0.912	+3.567	<.001	.005	3	1
COAD	CYCSP35 →	+0.229	+4.693	<.001	.007	3	1
COAD	VN1R105P →	+0.064	+5.251	<.001	.003	3	1
COAD	ALDH1L1-AS1 →	+0.198	+4.543	<.001	.005	3	1
COAD	RNU6-264P →	+0.417	+5.392	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

RNA5SP413 by NDUFS6 expression — LUSC

Explore this box plot interactively →