NDUFS6

Across TCGA cell cohorts, NDUFS6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,207 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NDUFS6-associated GO terms across cancer lineages are Meiotic recombination checkpoint signaling, Protein localization to nuclear inner membrane, and Proton motive force-driven ATP synthesis. Each is linked with NDUFS6 in more than 17 cancer types. Because this analysis shows association rather than direction, both NDUFS6-to-partner and partner-to-NDUFS6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic recombination checkpoint signaling grouped by NDUFS6-low versus NDUFS6-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS6→partner) and Y-score (partner→NDUFS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Meiotic recombination checkpoint signaling →	+0.249	+1.208	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Protein localization to nuclear inner membrane →	+0.142	+0.917	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Proton motive force-driven ATP synthesis →	+0.126	+1.239	<.001	<.001	3	10
BONE	Mitochondrial respiratory chain complex IV assembly →	+0.083	+0.700	.009	.006	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of nuclear division →	+0.094	+0.882	.001	<.001	3	10
BLOOD_Myeloma	DNA replication initiation →	+0.160	+0.937	.002	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,207 associations by consensus.

Meiotic recombination checkpoint signaling by NDUFS6 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →