NDUFS5P4

Across TCGA pan-cancer cohorts, NDUFS5P4 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated NDUFS5P4 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NDUFS5P4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NDUFS5P4 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LGG show a favorable association.

LUAD, KIRC, and SKCM are the cancer types where NDUFS5P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	II,III,IV	0.168	0.726	<.001	48	view →
KIRC	DFS	Tertile	IV	0.127	0.619	.008	36	view →
SKCM	OS	Tertile	All	0.197	0.871	<.001	36	view →
HNSC	OS	Tertile	II,III,IV	0.950	0.635	.008	36	view →
PRAD	OS	Tertile	All	0.942	0.996	.031	12	view →
ACC	DFS	Tertile	All	0.140	0.666	.049	9	view →
LGG	DFS	Tertile	All	0.949	0.821	.023	9	view →
BLCA	OS	Tertile	II,III,IV	1.000	0.708	.039	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

NDUFS5P4–LUAD (DFS)

Open the LUAD breakdown →