NDUFS5P4

Across TCGA pan-cancer cohorts, NDUFS5P4 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of NDUFS5P4’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where NDUFS5P4 RNA is repressed in tumor relative to normal tissue. In most cancer types NDUFS5P4 is over-expressed in tumor, although a few such as BRCA and ESCA show the opposite, repressed pattern.

BRCA and ESCA are the cancer types where NDUFS5P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NDUFS5P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	II,III,IV	−0.011	.046	4	view →
ESCA	Female	All	−0.286	<.001	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

NDUFS5P4–BRCA

Open the BRCA breakdown →