NDUFS5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NDUFS5 protein abundance is significantly associated with the RNA expression of many other genes, with 6,081 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NDUFS5-associated genes across cancer lineages are GJB1, PRKACB, and PLCL2. Each is linked with NDUFS5 in more than 3 cancer types. Because this analysis shows association rather than direction, both NDUFS5-to-partner and partner-to-NDUFS5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NDUFS5 versus GJB1 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS5→partner) and Y-score (partner→NDUFS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAGJB1 →+1.417+0.316<.001<.00134
COADPRKACB →+1.043+0.335<.001<.00133
HNSCPLCL2 →+0.898+0.430<.001<.00133
LUADMEX3A →-1.072-0.297<.001<.00133
GBMCALU →-0.573-0.343<.001<.00133
LUADPXDN →-0.983-0.293<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,081 associations by consensus.

NDUFS5 vs GJB1 — BRCA

Per-sample scatter of NDUFS5 vs GJB1 in BRCA (Pearson r = 0.36).

Explore this scatter interactively →

Exploration