NDUFS5

Across TCGA patient cohorts, NDUFS5 mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFS5-associated genes across cancer lineages are RNU6-597P, SPANXN5, and RNU6-921P. Each is linked with NDUFS5 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFS5-to-partner and partner-to-NDUFS5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-597P grouped by NDUFS5-low versus NDUFS5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS5→partner) and Y-score (partner→NDUFS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-597P →	+0.797	+2.863	<.001	.009	3	2
COAD	SPANXN5 →	+0.054	+5.080	.007	.008	3	1
COAD	RNU6-921P →	+0.531	+5.516	<.001	.004	3	1
COAD	RNU6-389P →	+0.620	+5.017	<.001	.009	3	1
COAD	SNRPGP1 →	+0.248	+5.790	.008	.003	3	1
COAD	LINC02565 →	+0.319	+5.080	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

RNU6-597P by NDUFS5 expression — UCEC

Explore this box plot interactively →