Across TCGA patient cohorts, NDUFS3 mutation is significantly associated with the RNA expression of many other genes, with 169 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFS3-associated genes across cancer lineages are EIF4A1P6, RNU6-406P, and USP17L8. Each is linked with NDUFS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFS3-to-partner and partner-to-NDUFS3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS3→partner) and Y-score (partner→NDUFS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EIF4A1P6 →	+0.233	+3.550	<.001	.005	3	2
UCEC	RNU6-406P →	+0.334	+2.754	.001	.007	3	2
PRAD	USP17L8 →	+0.014	+7.939	<.001	.008	3	1
PRAD	RN7SL727P →	+0.119	+7.939	<.001	.008	3	1
BRCA	MIR3648-2 →	+0.074	+7.473	<.001	.007	3	1
SKCM	OR7E53P →	+0.048	+5.292	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 169 associations by consensus.

Exploration

NDUFS3 survival (RNA) · tumor vs normal (RNA) · all NDUFS3 data types