NDUFS2

Across TCGA patient cohorts, NDUFS2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,508 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NDUFS2-associated genes across cancer lineages are AK3P3, CMTM3, and SEMA3C. Each is linked with NDUFS2 in more than 3 cancer types. Because this analysis shows association rather than direction, both NDUFS2-to-partner and partner-to-NDUFS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NDUFS2 versus AK3P3 in LUAD, with a Pearson correlation of -0.24.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS2→partner) and Y-score (partner→NDUFS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	AK3P3 →	-0.483	-0.147	.003	.006	3	4
BRCA	CMTM3 →	-0.552	-0.162	<.001	<.001	3	4
BRCA	SEMA3C →	-1.504	-0.210	<.001	<.001	3	4
BRCA	BICC1 →	-0.833	-0.162	<.001	<.001	3	4
LSCC	ADAMTS10 →	-0.781	-0.256	<.001	<.001	3	4
LSCC	VIM →	-0.975	-0.258	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,508 associations by consensus.

NDUFS2 vs AK3P3 — LUAD

Explore this scatter interactively →