NDUFS2

Across TCGA cell cohorts, NDUFS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,189 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NDUFS2-associated GO terms across cancer lineages are Aminoacyl-tRNA metabolism involved in translational fidelity, Tetrapyrrole metabolic process, and Tetrapyrrole biosynthetic process. Each is linked with NDUFS2 in more than 12 cancer types. Because this analysis shows association rather than direction, both NDUFS2-to-partner and partner-to-NDUFS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aminoacyl-tRNA metabolism involved in translational fidelity grouped by NDUFS2-low versus NDUFS2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS2→partner) and Y-score (partner→NDUFS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.117	+0.740	.002	<.001	3	13
PANCREAS	Tetrapyrrole metabolic process →	+0.106	+0.587	<.001	.001	3	12
BLOOD_Leukemia	Tetrapyrrole biosynthetic process →	+0.130	+0.796	<.001	<.001	3	12
BLOOD_Leukemia	Porphyrin-containing compound biosynthetic process →	+0.130	+0.796	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Threonyl-tRNA aminoacylation →	+0.193	+0.676	<.001	<.001	3	11
BLOOD_Leukemia	Heme biosynthetic process →	+0.124	+0.883	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,189 associations by consensus.

Aminoacyl-tRNA metabolism involved in translational fidelity by NDUFS2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →