NDUFS1

Across TCGA patient cohorts, NDUFS1 mutation is significantly associated with the RNA expression of many other genes, with 5,026 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFS1-associated genes across cancer lineages are LINC00609, OXSM, and VN1R7P. Each is linked with NDUFS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NDUFS1-to-partner and partner-to-NDUFS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00609 grouped by NDUFS1-low versus NDUFS1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS1→partner) and Y-score (partner→NDUFS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	LINC00609 →	+0.282	+3.070	<.001	.005	3	3
UCEC	OXSM →	+0.313	+2.502	<.001	.001	3	3
BRCA	VN1R7P →	+0.123	+5.378	<.001	.006	3	2
LUAD	OR2L3 →	+0.060	+4.631	<.001	.008	3	2
LUAD	PHKG1P3 →	+0.090	+5.912	<.001	.001	3	2
CESC	MIR196A2 →	+0.569	+4.200	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,026 associations by consensus.

LINC00609 by NDUFS1 expression — LUSC

Explore this box plot interactively →