NDUFS1

Across TCGA cell cohorts, NDUFS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,565 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NDUFS1-associated GO terms across cancer lineages are DNA-templated DNA replication maintenance of fidelity, Centrosome duplication, and Pyruvate decarboxylation to acetyl-CoA. Each is linked with NDUFS1 in more than 12 cancer types. Because this analysis shows association rather than direction, both NDUFS1-to-partner and partner-to-NDUFS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication maintenance of fidelity grouped by NDUFS1-low versus NDUFS1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS1→partner) and Y-score (partner→NDUFS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA-templated DNA replication maintenance of fidelity →	+0.098	+1.027	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Centrosome duplication →	+0.078	+0.960	.003	<.001	3	13
PANCREAS	Pyruvate decarboxylation to acetyl-CoA →	+0.129	+0.684	.005	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Centrosome cycle →	+0.066	+0.953	.005	.004	3	13
SKIN	Cytosolic transport →	+0.064	+0.742	<.001	<.001	3	12
URINARY_TRACT	Defense response to bacterium →	-0.118	-0.725	.002	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,565 associations by consensus.

DNA-templated DNA replication maintenance of fidelity by NDUFS1 expression — SOFT_TISSUE

Explore this box plot interactively →