NDUFC1

Across TCGA cell cohorts, NDUFC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,845 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible NDUFC1-associated GO terms across cancer lineages are Regulation of Rho protein signal transduction, Regulation of cell morphogenesis, and U1 snRNA 3'-end processing. Each is linked with NDUFC1 in more than 10 cancer types. Because this analysis shows association rather than direction, both NDUFC1-to-partner and partner-to-NDUFC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of Rho protein signal transduction grouped by NDUFC1-low versus NDUFC1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFC1→partner) and Y-score (partner→NDUFC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of Rho protein signal transduction →	-0.082	-0.595	<.001	.002	3	11
STOMACH	Regulation of cell morphogenesis →	-0.055	-0.786	<.001	.002	3	10
LUNG_NSCLC_LUSC	U1 snRNA 3'-end processing →	+0.137	+0.726	<.001	<.001	3	10
LUNG_NSCLC_LUSC	U5 snRNA 3'-end processing →	+0.137	+0.726	<.001	<.001	3	10
URINARY_TRACT	DAMP biosynthetic process →	+0.151	+0.846	<.001	.002	2	11
URINARY_TRACT	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.151	+0.846	<.001	.002	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,845 associations by consensus.

Regulation of Rho protein signal transduction by NDUFC1 expression — PANCREAS

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