NDUFB7

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NDUFB7 mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFB7-associated genes across cancer lineages are RNU6-470P, UBE2V1P4, and YBX1P9. Each is linked with NDUFB7 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFB7-to-partner and partner-to-NDUFB7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-470P grouped by NDUFB7-low versus NDUFB7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFB7→partner) and Y-score (partner→NDUFB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-470P →+0.432+4.538<.001.00632
CESCUBE2V1P4 →+0.127+5.103<.001.00831
CESCYBX1P9 →+0.070+5.010<.001.00931
CESCMTND2P8 →+0.043+5.418<.001.00531
CESCELAVL4-AS1 →+0.054+5.103.003.00831
CESCMEMO1P3 →+0.178+5.201<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

RNU6-470P by NDUFB7 expression — UCEC

Box plot of RNU6-470P in NDUFB7-low vs NDUFB7-high samples in UCEC.

Explore this box plot interactively →

Exploration