NDUFB6

Across TCGA pan-cancer cohorts, NDUFB6 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NDUFB6 data layer compared with 19 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NDUFB6 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NDUFB6 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and OV show a favorable association.

CCRCC, OV, and LUAD are the cancer types where NDUFB6 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	0.881	0.671	.005	10	view →
OV	DFS	Quartile	All	0.819	0.472	.042	8	view →
LUAD	DFS	Quartile	III,IV	0.768	0.283	.035	2	view →
LSCC	DFS	Tertile	II,III,IV	0.498	1.000	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NDUFB6–CCRCC (DFS)

Open the CCRCC breakdown →