NDUFB6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NDUFB6 mutation is significantly associated with the RNA expression of many other genes, with 59 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFB6-associated genes across cancer lineages are RBM17P2, RNA5SP414, and MIR7702. Each is linked with NDUFB6 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFB6-to-partner and partner-to-NDUFB6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBM17P2 grouped by NDUFB6-low versus NDUFB6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFB6→partner) and Y-score (partner→NDUFB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRBM17P2 →+0.032+4.027.007.00131
UCECRNA5SP414 →+0.794+2.933<.001.00631
UCECMIR7702 →+0.415+5.253<.001.00131
UCECAQP7P2 →+0.242+3.010<.001.00231
UCECAQP7P1 →+0.884+3.692<.001.00231
UCECMIR367 →+0.579+2.783<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

RBM17P2 by NDUFB6 expression — UCEC

Box plot of RBM17P2 in NDUFB6-low vs NDUFB6-high samples in UCEC.

Explore this box plot interactively →

Exploration