NDUFB5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NDUFB5 mutation is significantly associated with the RNA expression of many other genes, with 101 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFB5-associated genes across cancer lineages are RNA5SP411, RNA5SP419, and NKAIN1P1. Each is linked with NDUFB5 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFB5-to-partner and partner-to-NDUFB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by NDUFB5-low versus NDUFB5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFB5→partner) and Y-score (partner→NDUFB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP411 →+2.275+3.393<.001.00732
UCECRNA5SP419 →+1.819+4.077<.001.00132
LUADNKAIN1P1 →+0.101+5.197<.001.00332
LUADLINC01895 →+1.491+4.659<.001.00432
SKCMRNU6-290P →+0.241+4.884<.001.00432
BRCAANKRD20A6P →+0.153+8.055<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 101 associations by consensus.

RNA5SP411 by NDUFB5 expression — UCEC

Box plot of RNA5SP411 in NDUFB5-low vs NDUFB5-high samples in UCEC.

Explore this box plot interactively →

Exploration