NDUFB4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NDUFB4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,134 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NDUFB4-associated GO terms across cancer lineages are Calcium-independent cell-matrix adhesion, Negative regulation of translational initiation, and Regulation of intracellular protein transport. Each is linked with NDUFB4 in more than 10 cancer types. Because this analysis shows association rather than direction, both NDUFB4-to-partner and partner-to-NDUFB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium-independent cell-matrix adhesion grouped by NDUFB4-low versus NDUFB4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFB4→partner) and Y-score (partner→NDUFB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONECalcium-independent cell-matrix adhesion →-0.200-0.656<.001.001311
PANCREASNegative regulation of translational initiation →-0.093-0.730<.001<.001310
UPPER_AERODIGESTIVE_TRACTRegulation of intracellular protein transport →-0.089-0.854<.001.00139
BONEMitochondrial translational elongation →+0.138+0.579<.001.006210
BONEGolgi lumen acidification →+0.106+0.820<.001.00239
SKINResponse to dehydroepiandrosterone →-0.204-0.468.009<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,134 associations by consensus.

Calcium-independent cell-matrix adhesion by NDUFB4 expression — BONE

Box plot of Calcium-independent cell-matrix adhesion in NDUFB4-low vs NDUFB4-high samples in BONE.

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Exploration