NDUFB10

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NDUFB10 mutation is significantly associated with the RNA expression of many other genes, with 61 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFB10-associated genes across cancer lineages are RPL18P1, MIR8082, and RPS29P32. Each is linked with NDUFB10 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFB10-to-partner and partner-to-NDUFB10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL18P1 grouped by NDUFB10-low versus NDUFB10-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFB10→partner) and Y-score (partner→NDUFB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRPL18P1 →+0.335+4.542<.001.00132
UCECMIR8082 →+0.815+4.146<.001.00331
UCECRPS29P32 →+0.678+4.184.001.00331
LIHCLINC00561 →+0.032+6.149<.001.00231
LIHCMIR4757 →+0.535+6.305<.001.00131
BLCAMIR4714 →+0.658+4.299<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 61 associations by consensus.

RPL18P1 by NDUFB10 expression — COAD

Box plot of RPL18P1 in NDUFB10-low vs NDUFB10-high samples in COAD.

Explore this box plot interactively →

Exploration