NDUFB10

Across TCGA pan-cancer cohorts, NDUFB10 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of NDUFB10’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where NDUFB10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NDUFB10 is over-expressed in tumor.

KIRC, LIHC, and KIRP are the cancer types where NDUFB10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NDUFB10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	III,IV	+0.315	<.001	9	view →
LIHC	All	II,III,IV	+0.711	<.001	8	view →
KIRP	All	II,III,IV	+0.588	<.001	7	view →
BRCA	All	III,IV	+0.515	<.001	6	view →
LUSC	All	II,III,IV	+0.393	<.001	5	view →
LUAD	All	All	+0.265	.002	4	view →
CHOL	All	All	+0.811	<.001	3	view →
PRAD	All	All	+0.236	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

NDUFB10–KIRC

Open the KIRC breakdown →