Across TCGA patient cohorts, NDUFB1 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFB1-associated genes across cancer lineages are PPP3R2, RNU6-173P, and GYG2P1. Each is linked with NDUFB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFB1-to-partner and partner-to-NDUFB1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFB1→partner) and Y-score (partner→NDUFB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPP3R2 →	+0.082	+3.863	.001	.008	3	1
UCEC	RNU6-173P →	+0.469	+4.352	<.001	.008	3	1
UCEC	GYG2P1 →	+0.109	+4.648	<.001	.001	3	1
UCEC	PGGT1BP2 →	+0.144	+3.879	.005	.008	3	1
UCEC	HMGB3P20 →	+0.240	+3.911	<.001	.007	3	1
UCEC	FDX1P2 →	+0.237	+4.386	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

NDUFB1 survival (RNA) · tumor vs normal (RNA) · all NDUFB1 data types