NDUFAF4P4

Across TCGA pan-cancer cohorts, NDUFAF4P4 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated NDUFAF4P4 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher NDUFAF4P4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NDUFAF4P4 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LAML show a favorable association.

LIHC, READ, and SKCM are the cancer types where NDUFAF4P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Tertile	All	0.202	0.454	<.001	63	view →
READ	OS	Tertile	III,IV	0.289	0.932	<.001	27	view →
SKCM	DFS	Tertile	II,III,IV	0.422	0.582	.011	24	view →
KIRP	DFS	Tertile	All	0.693	0.885	.004	21	view →
GBM	DFS	Quartile	All	0.139	0.273	.005	18	view →
BRCA	OS	Tertile	IV	1.000	0.638	.039	9	view →
CHOL	OS	Tertile	All	0.136	0.710	.005	9	view →
ACC	OS	Tertile	II,III,IV	0.268	0.788	.028	9	view →
PCPG	OS	Tertile	All	0.817	0.977	.032	9	view →
LAML	DFS	Median	All	0.463	0.290	.019	6	view →
STAD	OS	Median	IV	0.561	0.184	.016	3	view →
LUSC	DFS	Quartile	All	0.314	0.572	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

NDUFAF4P4–LIHC (DFS)

Open the LIHC breakdown →