Across TCGA pan-cancer cohorts, NDUFAF4P4 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of NDUFAF4P4’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where NDUFAF4P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NDUFAF4P4 is over-expressed in tumor.
BRCA, LUAD, and LUSC are the cancer types where NDUFAF4P4 tumor–normal differential expression is most reproducible.