NDUFAF4

Across TCGA patient cohorts, NDUFAF4 protein abundance is significantly associated with the RNA expression of many other genes, with 18,156 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NDUFAF4-associated genes across cancer lineages are ZNF25, DSE, and PLAU. Each is linked with NDUFAF4 in more than 5 cancer types. Because this analysis shows association rather than direction, both NDUFAF4-to-partner and partner-to-NDUFAF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NDUFAF4 versus ZNF25 in BRCA, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFAF4→partner) and Y-score (partner→NDUFAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF25 →	-0.550	-0.422	<.001	<.001	3	6
BRCA	DSE →	-0.653	-0.366	<.001	.006	3	6
OV	PLAU →	-1.276	-0.442	.001	<.001	3	6
OV	JCAD →	-0.860	-0.406	.002	.003	3	6
OV	NRP1 →	-1.072	-0.607	<.001	<.001	3	6
OV	MYOF →	-0.920	-0.402	.001	.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,156 associations by consensus.

NDUFAF4 vs ZNF25 — BRCA

Explore this scatter interactively →