NDUFAF1

Across TCGA cell cohorts, NDUFAF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,345 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NDUFAF1-associated GO terms across cancer lineages are Circadian sleep/wake cycle, Ubiquitin-dependent protein catabolic process via the N-end rule pathway, and Endodermal cell fate commitment. Each is linked with NDUFAF1 in more than 13 cancer types. Because this analysis shows association rather than direction, both NDUFAF1-to-partner and partner-to-NDUFAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Circadian sleep/wake cycle grouped by NDUFAF1-low versus NDUFAF1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFAF1→partner) and Y-score (partner→NDUFAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Circadian sleep/wake cycle →	+0.164	+0.849	.005	.001	2	14
OESOPHAGUS	Ubiquitin-dependent protein catabolic process via the N-end rule pathway →	+0.113	+0.946	<.001	.003	3	13
BLOOD_Leukemia	Endodermal cell fate commitment →	+0.131	+0.622	<.001	<.001	3	11
OVARY	snRNA processing →	+0.075	+0.757	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Intracellular magnesium ion homeostasis →	+0.097	+0.459	.009	.005	2	10
OVARY	mRNA pseudouridine synthesis →	+0.082	+0.704	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,345 associations by consensus.

Circadian sleep/wake cycle by NDUFAF1 expression — LIVER

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