NDUFA9

Across TCGA patient cohorts, NDUFA9 mutation is significantly associated with the RNA expression of many other genes, with 1,595 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFA9-associated genes across cancer lineages are OR11H12, ICOS, and HSPA4L. Each is linked with NDUFA9 in more than 2 cancer types. Because this analysis shows association rather than direction, both NDUFA9-to-partner and partner-to-NDUFA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H12 grouped by NDUFA9-low versus NDUFA9-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFA9→partner) and Y-score (partner→NDUFA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OR11H12 →	+0.067	+5.324	<.001	.003	3	2
UCEC	ICOS →	+0.728	+3.108	<.001	<.001	3	2
UCEC	HSPA4L →	+0.883	+2.823	<.001	.001	3	2
UCEC	CLEC12A →	+0.461	+3.749	<.001	<.001	3	2
UCEC	RABEP1 →	+0.393	+2.425	.007	.002	3	2
UCEC	NUP50 →	+0.449	+2.415	.004	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,595 associations by consensus.

OR11H12 by NDUFA9 expression — BRCA

Explore this box plot interactively →