NDUFA7

Across TCGA patient cohorts, NDUFA7 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFA7-associated genes across cancer lineages are MIR3180-4, RNU6-586P, and DEFB103A. Each is linked with NDUFA7 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFA7-to-partner and partner-to-NDUFA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3180-4 grouped by NDUFA7-low versus NDUFA7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFA7→partner) and Y-score (partner→NDUFA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR3180-4 →	+0.341	+4.641	<.001	.006	3	2
BLCA	RNU6-586P →	+0.593	+7.640	<.001	.009	3	1
BRCA	DEFB103A →	+0.059	+8.055	<.001	.007	3	1
BRCA	TRGV8 →	+0.064	+7.731	<.001	.009	3	1
BRCA	CDY22P →	+0.024	+8.471	<.001	.005	3	1
BRCA	RNU6-1037P →	+0.312	+8.471	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

MIR3180-4 by NDUFA7 expression — UCEC

Explore this box plot interactively →