NDUFA7

Across TCGA pan-cancer cohorts, NDUFA7 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated NDUFA7 data layer compared with 6 for mutation status.

The strongest signal is observed in uveal melanoma (UVM), where higher NDUFA7 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NDUFA7 expression acts as an unfavorable survival marker, although some lineages such as CESC and BLCA show a favorable association.

UVM, ACC, and KICH are the cancer types where NDUFA7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	II,III,IV	0.335	0.721	.003	85	view →
ACC	DFS	Median	All	0.241	0.675	<.001	73	view →
KICH	DFS	Quartile	All	0.405	1.000	.003	54	view →
CESC	DFS	Quartile	II,III,IV	0.818	0.366	.002	50	view →
UCS	DFS	Median	IV	0.367	0.952	.001	44	view →
LIHC	OS	Quartile	III,IV	0.361	0.809	.003	36	view →
BLCA	DFS	Quartile	All	0.541	0.398	.015	22	view →
LUSC	DFS	Tertile	All	0.499	0.318	.012	20	view →
KIRP	OS	Median	All	0.871	0.606	.007	18	view →
ESCA	DFS	Median	III,IV	0.331	0.547	.017	16	view →
SKCM	OS	Quartile	All	0.203	0.533	.002	14	view →
DLBC	OS	Tertile	II,III,IV	0.279	1.000	.025	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

NDUFA7–UVM (DFS)

Open the UVM breakdown →