NDUFA6-DT

Across TCGA pan-cancer cohorts, NDUFA6-DT RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated NDUFA6-DT data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NDUFA6-DT RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated NDUFA6-DT expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

HNSC, BRCA, and ACC are the cancer types where NDUFA6-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.804	0.632	.001	77	view →
BRCA	DFS	Tertile	III,IV	0.896	0.712	.001	71	view →
ACC	DFS	Tertile	All	0.196	0.743	<.001	50	view →
PAAD	DFS	Quartile	All	0.479	0.218	<.001	43	view →
LGG	OS	Median	All	0.876	0.740	<.001	43	view →
UVM	OS	Quartile	III,IV	0.496	1.000	.006	38	view →
MESO	OS	Median	All	0.719	0.302	.003	30	view →
PRAD	DFS	Median	All	0.842	0.923	.003	18	view →
KIRP	DFS	Median	All	0.900	0.604	.002	17	view →
READ	OS	Median	III,IV	0.673	0.317	.008	16	view →
UCEC	OS	Median	All	0.699	0.658	.017	16	view →
GBM	OS	Tertile	All	0.629	0.259	<.001	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

NDUFA6-DT–HNSC (DFS)

Open the HNSC breakdown →