NDUFA6-DT

Across TCGA pan-cancer cohorts, NDUFA6-DT RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of NDUFA6-DT’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where NDUFA6-DT RNA is repressed in tumor relative to normal tissue. In most cancer types NDUFA6-DT is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and THCA are the cancer types where NDUFA6-DT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NDUFA6-DT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.371	<.001	12	view →
KICH	All	IV	−0.895	<.001	11	view →
THCA	Male	III,IV	−0.805	<.001	11	view →
KIRP	Male	All	−0.445	<.001	7	view →
UCEC	All	All	−0.436	<.001	6	view →
READ	All	II,III,IV	−0.422	.004	5	view →
COAD	All	II,III,IV	−0.231	<.001	5	view →
CHOL	All	II,III,IV	−1.330	.010	4	view →
LUSC	All	All	+0.321	<.001	4	view →
BLCA	Male	IV	−0.530	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

NDUFA6-DT–KIRC

Open the KIRC breakdown →