NDUFA5

Across TCGA patient cohorts, NDUFA5 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFA5-associated genes across cancer lineages are Ku80, MEK1, and 4E-BP1_pT37_T46. Each is linked with NDUFA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFA5-to-partner and partner-to-NDUFA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by NDUFA5-low versus NDUFA5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFA5→partner) and Y-score (partner→NDUFA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.329	+3.183	.011	.010	3	1
UCEC	MEK1 →	+0.437	+3.169	.029	.019	3	1
UCEC	4E-BP1_pT37_T46 →	-0.512	-3.169	.013	.020	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Ku80 by NDUFA5 expression — UCEC

Explore this box plot interactively →