NDUFA10

Across TCGA patient cohorts, NDUFA10 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFA10-associated genes across cancer lineages are MEK1, p62 Lck ligand, and PDCD4. Each is linked with NDUFA10 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFA10-to-partner and partner-to-NDUFA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by NDUFA10-low versus NDUFA10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFA10→partner) and Y-score (partner→NDUFA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.354	+2.222	.022	.011	3	2
UCEC	p62 Lck ligand →	+0.326	+2.222	.018	.011	3	2
UCEC	PDCD4 →	-0.494	-3.169	.013	.018	3	2
UCEC	PRDX1 →	+0.190	+2.459	.029	.019	3	2
UCEC	S6_pS240_S244 →	+0.375	+1.700	.029	.044	3	2
UCEC	VHL →	-1.112	-2.115	<.001	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

MEK1 by NDUFA10 expression — UCEC

Explore this box plot interactively →