NDST4

Across TCGA patient cohorts, NDST4 mutation is significantly associated with the total protein of many other genes, with 68 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDST4-associated genes across cancer lineages are TFRC, Cyclin-B1, and FASN. Each is linked with NDST4 in more than 2 cancer types. Because this analysis shows association rather than direction, both NDST4-to-partner and partner-to-NDST4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by NDST4-low versus NDST4-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDST4→partner) and Y-score (partner→NDST4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TFRC →	+0.526	+3.000	.005	.034	3	3
UCEC	Cyclin-B1 →	+0.632	+3.700	<.001	.001	3	3
LUSC	FASN →	+0.400	+1.687	.008	.013	3	3
UCEC	JNK_pT183_Y185 →	-0.184	-2.321	<.001	.005	3	3
SKCM	TSC1 →	-0.124	-1.180	.021	.005	3	3
UCEC	FoxM1 →	+0.188	+1.777	.022	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

TFRC by NDST4 expression — LUAD

Explore this box plot interactively →