NDST4

Across TCGA pan-cancer cohorts, NDST4 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of NDST4’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where NDST4 RNA is repressed in tumor relative to normal tissue. In most cancer types NDST4 is over-expressed in tumor, although a few such as KICH and READ show the opposite, repressed pattern.

KICH, BRCA, and READ are the cancer types where NDST4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NDST4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.025	.005	6	view →
BRCA	Female	II,III,IV	+0.364	.002	4	view →
READ	All	III,IV	−0.100	.009	4	view →
KIRC	Male	All	−0.016	<.001	4	view →
COAD	Female	IV	−0.160	.003	3	view →
HNSC	Female	IV	−0.038	.022	3	view →
STAD	All	All	−0.191	.022	2	view →
KIRP	Female	All	−0.024	.040	1	view →
LUSC	All	III,IV	−0.021	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

NDST4–KICH

Open the KICH breakdown →