NDST4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NDST4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,080 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NDST4-associated GO terms across cancer lineages are Sterol biosynthetic process, Secondary alcohol biosynthetic process, and Cholesterol biosynthetic process via desmosterol. Each is linked with NDST4 in more than 4 cancer types. Because this analysis shows association rather than direction, both NDST4-to-partner and partner-to-NDST4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sterol biosynthetic process grouped by NDST4-low versus NDST4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDST4→partner) and Y-score (partner→NDST4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONESterol biosynthetic process →+0.162+1.904<.001.00135
LUNG_SCLCSecondary alcohol biosynthetic process →+0.201+1.584<.001.00235
LUNG_SCLCCholesterol biosynthetic process via desmosterol →+0.221+1.705<.001<.00135
BONECholesterol biosynthetic process via lathosterol →+0.210+2.188<.001<.00135
LUNG_SCLCZymosterol metabolic process →+0.259+1.506<.001<.00135
LUNG_SCLCZymosterol biosynthetic process →+0.259+1.506<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,080 associations by consensus.

Sterol biosynthetic process by NDST4 expression — BONE

Box plot of Sterol biosynthetic process in NDST4-low vs NDST4-high samples in BONE.

Explore this box plot interactively →

Exploration