NDST4

Across TCGA cell cohorts, NDST4 mutation is significantly associated with the RNA expression of many other genes, with 301 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NDST4-associated genes across cancer lineages are TMPRSS12, DMRTC1, and DNAAF6. Each is linked with NDST4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDST4-to-partner and partner-to-NDST4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMPRSS12 grouped by NDST4-low versus NDST4-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDST4→partner) and Y-score (partner→NDST4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	TMPRSS12 →	+0.026	+2.584	<.001	.004	3	2
BLOOD_Leukemia	DMRTC1 →	+0.289	+3.855	<.001	.007	3	2
BLOOD_Leukemia	DNAAF6 →	+0.037	+3.847	<.001	.007	3	2
LARGE_INTESTINE	ZCCHC2 →	+0.959	+3.389	<.001	.001	3	2
OESOPHAGUS	SLC5A8 →	+0.070	+4.906	<.001	.006	3	1
BLOOD_Myeloma	IFNA5 →	+0.024	+3.906	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 301 associations by consensus.

TMPRSS12 by NDST4 expression — LUNG_SCLC

Explore this box plot interactively →