NDST3

Across TCGA patient cohorts, NDST3 mutation is significantly associated with the RNA expression of many other genes, with 4,457 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDST3-associated genes across cancer lineages are RCC1, RNMTL1P2, and SUPV3L1. Each is linked with NDST3 in more than 3 cancer types. Because this analysis shows association rather than direction, both NDST3-to-partner and partner-to-NDST3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RCC1 grouped by NDST3-low versus NDST3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDST3→partner) and Y-score (partner→NDST3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RCC1 →	+0.423	+2.673	<.001	<.001	3	4
COAD	RNMTL1P2 →	+0.064	+3.385	.001	.004	3	3
UCEC	SUPV3L1 →	+0.475	+2.818	<.001	<.001	3	3
UCEC	DDX19B →	+0.347	+1.870	<.001	<.001	3	3
UCEC	CDC25C →	+0.570	+1.827	<.001	<.001	3	3
UCEC	DONSON →	+0.553	+1.784	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,457 associations by consensus.

RCC1 by NDST3 expression — UCEC

Explore this box plot interactively →