NDST2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NDST2 mutation is significantly associated with the RNA expression of many other genes, with 4,113 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDST2-associated genes across cancer lineages are RNU6-440P, GRPEL2P2, and LINC02531. Each is linked with NDST2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NDST2-to-partner and partner-to-NDST2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-440P grouped by NDST2-low versus NDST2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDST2→partner) and Y-score (partner→NDST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCRNU6-440P →+0.147+5.596.003.00133
LUSCGRPEL2P2 →+0.063+4.347.001<.00133
CESCLINC02531 →+0.258+3.366<.001.00632
COADMIR378E →+0.631+4.721<.001.00432
SKCMMIR5192 →+0.516+3.823<.001.00132
HNSCFABP5P15 →+0.181+5.241<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,113 associations by consensus.

RNU6-440P by NDST2 expression — LUSC

Box plot of RNU6-440P in NDST2-low vs NDST2-high samples in LUSC.

Explore this box plot interactively →

Exploration