NDST2

Across TCGA patient cohorts, NDST2 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDST2-associated genes across cancer lineages are ATM, c-Met_pY1235, and Ku80. Each is linked with NDST2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NDST2-to-partner and partner-to-NDST2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by NDST2-low versus NDST2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDST2→partner) and Y-score (partner→NDST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.484	-2.308	.001	.005	3	3
UCEC	c-Met_pY1235 →	+0.050	+1.290	.042	.034	3	3
UCEC	Ku80 →	+0.157	+1.598	.047	.006	3	2
UCEC	C-Raf →	+0.122	+1.584	.011	.009	3	2
UCEC	JNK2 →	+0.220	+1.901	<.001	.028	3	1
UCEC	MEK1 →	+0.356	+1.807	.003	.024	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

ATM by NDST2 expression — UCEC

Explore this box plot interactively →