NDST1

Across TCGA pan-cancer cohorts, NDST1 Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated NDST1 data layer compared with 26 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher NDST1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NDST1 expression acts as an unfavorable survival marker.

OV, DLBC, and HNSC are the cancer types where NDST1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.023	0.844	<.001	36	view →
DLBC	OS	Median	II,III,IV	0.172	0.949	<.001	30	view →
HNSC	OS	Median	All	0.156	0.710	.002	30	view →
UCEC	OS	Median	IV	0.225	0.772	<.001	12	view →
SKCM	OS	Median	All	0.348	0.784	.008	9	view →
SARC	DFS	Median	All	0.121	0.611	.041	6	view →
PRAD	DFS	Median	All	0.085	0.774	.004	6	view →
LGG	DFS	Median	All	0.249	0.728	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

NDST1–OV (OS)

Open the OV breakdown →