NDST1

Across TCGA patient cohorts, NDST1 mutation is significantly associated with the RNA expression of many other genes, with 6,223 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDST1-associated genes across cancer lineages are EIF2B2, ZFPL1, and LRRC59. Each is linked with NDST1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NDST1-to-partner and partner-to-NDST1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EIF2B2 grouped by NDST1-low versus NDST1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDST1→partner) and Y-score (partner→NDST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EIF2B2 →	+0.361	+2.434	<.001	<.001	3	4
UCEC	ZFPL1 →	+0.360	+2.850	<.001	<.001	3	4
UCEC	LRRC59 →	+0.576	+1.970	<.001	<.001	3	3
UCEC	NDUFC1 →	+0.324	+1.606	<.001	<.001	3	3
UCEC	TPI1 →	+0.424	+1.959	<.001	<.001	3	3
UCEC	FANCE →	+0.448	+2.202	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,223 associations by consensus.

EIF2B2 by NDST1 expression — UCEC

Explore this box plot interactively →