NDST1

Across TCGA patient cohorts, NDST1 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDST1-associated genes across cancer lineages are Caspase-7-cleavedD198, 4E-BP1, and Notch1. Each is linked with NDST1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NDST1-to-partner and partner-to-NDST1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by NDST1-low versus NDST1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDST1→partner) and Y-score (partner→NDST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.667	+1.756	<.001	.003	3	3
UCEC	4E-BP1 →	+0.234	+2.117	.004	.002	3	3
UCEC	Notch1 →	+0.121	+1.754	.004	.001	3	2
UCEC	Rictor_pT1135 →	-0.084	-1.662	.006	.010	3	2
UCEC	STAT3_pY705 →	-0.232	-1.280	.003	.049	3	2
UCEC	TFRC →	+0.447	+2.807	.005	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Caspase-7-cleavedD198 by NDST1 expression — UCEC

Explore this box plot interactively →