NDST1

Across TCGA cell cohorts, NDST1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,676 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NDST1-associated GO terms across cancer lineages are Negative regulation of Rho protein signal transduction, Regulation of cell-substrate adhesion, and Regulation of cell-matrix adhesion. Each is linked with NDST1 in more than 15 cancer types. Because this analysis shows association rather than direction, both NDST1-to-partner and partner-to-NDST1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of Rho protein signal transduction grouped by NDST1-low versus NDST1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDST1→partner) and Y-score (partner→NDST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of Rho protein signal transduction →	+0.185	+1.818	<.001	<.001	3	16
BONE	Regulation of cell-substrate adhesion →	+0.120	+1.502	<.001	<.001	3	15
BONE	Regulation of cell-matrix adhesion →	+0.143	+1.581	<.001	<.001	3	14
STOMACH	Regulation of hippo signaling →	+0.108	+2.070	<.001	<.001	3	14
BONE	Positive regulation of transforming growth factor beta receptor signaling pathway →	+0.183	+2.319	<.001	<.001	3	14
BONE	Positive regulation of cellular response to transforming growth factor beta stimulus →	+0.183	+2.319	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,676 associations by consensus.

Negative regulation of Rho protein signal transduction by NDST1 expression — BONE

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