NDST1

Across TCGA cell cohorts, NDST1 mutation is significantly associated with the RNA expression of many other genes, with 151 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NDST1-associated genes across cancer lineages are EDAR, KRTAP21-2, and OR2A2. Each is linked with NDST1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDST1-to-partner and partner-to-NDST1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EDAR grouped by NDST1-low versus NDST1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDST1→partner) and Y-score (partner→NDST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	EDAR →	+0.200	+3.793	<.001	.007	3	2
LARGE_INTESTINE	KRTAP21-2 →	+0.036	+2.345	<.001	.007	3	2
URINARY_TRACT	OR2A2 →	+0.046	+5.087	<.001	.004	3	1
UPPER_AERODIGESTIVE_TRACT	FAM236A →	+0.120	+5.357	<.001	.003	3	1
BLOOD_Leukemia	ELMOD1 →	+0.150	+3.727	.003	.008	3	1
BLOOD_Leukemia	PACRG →	+0.309	+3.769	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 151 associations by consensus.

EDAR by NDST1 expression — BLOOD_Leukemia

Explore this box plot interactively →