NDRG4

Across TCGA patient cohorts, NDRG4 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,958 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NDRG4-associated proteins across cancer lineages are CLASP1, MAP1A, and MLPH. Each is linked with NDRG4 in more than 6 cancer types. Because this analysis shows association rather than direction, both NDRG4-to-partner and partner-to-NDRG4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NDRG4 versus CLASP1 in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NDRG4→partner) and Y-score (partner→NDRG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CLASP1 →	+0.235	+1.139	<.001	<.001	3	7
LSCC	MAP1A →	+0.469	+1.076	.002	.003	3	5
BRCA	MLPH →	-0.876	-0.619	<.001	.001	3	5
BRCA	MMP14 →	+0.621	+0.670	<.001	<.001	3	5
UCEC	ARFIP1 →	-0.359	-0.675	<.001	<.001	3	5
BRCA	SGSM3 →	-0.563	-0.679	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,958 associations by consensus.

NDRG4 vs CLASP1 — LSCC

Explore this scatter interactively →