NDRG4

Across TCGA patient cohorts, NDRG4 protein abundance is significantly associated with the RNA expression of many other genes, with 12,518 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NDRG4-associated genes across cancer lineages are ELOVL4, CYP4F11, and ALOX12B. Each is linked with NDRG4 in more than 3 cancer types. Because this analysis shows association rather than direction, both NDRG4-to-partner and partner-to-NDRG4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NDRG4 versus ELOVL4 in HNSC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDRG4→partner) and Y-score (partner→NDRG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ELOVL4 →	+0.956	+0.697	<.001	<.001	3	4
LSCC	CYP4F11 →	+3.124	+0.878	<.001	<.001	3	4
HNSC	ALOX12B →	+1.513	+0.933	<.001	<.001	3	4
CCRCC	RAP1GAP →	+1.060	+0.524	<.001	.007	3	4
CCRCC	ACO2 →	+0.466	+0.675	.004	.007	3	4
GBM	NRXN2 →	+0.948	+0.373	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,518 associations by consensus.

NDRG4 vs ELOVL4 — HNSC

Explore this scatter interactively →