NDRG4

Across TCGA cell cohorts, NDRG4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,204 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NDRG4-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Protein stabilization, and Regulation of myoblast fusion. Each is linked with NDRG4 in more than 15 cancer types. Because this analysis shows association rather than direction, both NDRG4-to-partner and partner-to-NDRG4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by NDRG4-low versus NDRG4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDRG4→partner) and Y-score (partner→NDRG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.109	+1.810	<.001	<.001	3	15
STOMACH	Protein stabilization →	+0.078	+1.991	<.001	<.001	3	14
OVARY	Regulation of myoblast fusion →	+0.113	+1.673	<.001	<.001	3	14
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.120	+1.358	.007	.005	1	16
OESOPHAGUS	Macroautophagy →	+0.050	+1.348	.002	.003	3	13
OESOPHAGUS	Cytoplasmic translation →	+0.103	+1.695	.002	<.001	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,204 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by NDRG4 expression — OVARY

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