NDRG1

Across TCGA cell cohorts, NDRG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,558 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NDRG1-associated GO terms across cancer lineages are Peripheral nervous system myelin maintenance, Myelin maintenance, and Cellular response to steroid hormone stimulus. Each is linked with NDRG1 in more than 19 cancer types. Because this analysis shows association rather than direction, both NDRG1-to-partner and partner-to-NDRG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peripheral nervous system myelin maintenance grouped by NDRG1-low versus NDRG1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDRG1→partner) and Y-score (partner→NDRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Peripheral nervous system myelin maintenance →	+0.375	+2.860	<.001	<.001	3	20
BONE	Myelin maintenance →	+0.258	+2.935	<.001	<.001	3	16
KIDNEY	Cellular response to steroid hormone stimulus →	+0.099	+3.571	<.001	<.001	3	12
OVARY	Nuclear receptor-mediated steroid hormone signaling pathway →	+0.085	+2.451	<.001	<.001	3	11
OVARY	Steroid hormone receptor signaling pathway →	+0.085	+2.451	<.001	<.001	3	11
SOFT_TISSUE	Intracellular receptor signaling pathway →	+0.051	+3.700	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,558 associations by consensus.

Peripheral nervous system myelin maintenance by NDRG1 expression — BONE

Explore this box plot interactively →